Management Team
Dr. Robert F. Ryan, President and CEO:
Dr. Robert F. Ryan was named President and Chief Executive Officer. Dr. Ryan
has broad scientific experience in biochemistry, cell and molecular biology,
human genetics, novel therapies, and basic and clinical cancer research, having
received his Masters in Biochemistry, Cell and Molecular Biology at The Medical
College of Georgia, studying sickle cell anemia. He received his Ph.D. in
Molecular Genetics at Thomas Jefferson University characterizing DNA and RNA
binding properties of zinc finger proteins. Through his extensive training, his
experiences extend across the fields of aging, hemoglobinopathies, gene
expression, human diseases, DNA, RNA, proteins and their interactions, stem cell
research and applications, oncology, clinical protocols and therapies.
Professionally, Dr. Ryan has become a pioneer in the field of emerging
biotechnology, specializing in assisting small companies with insight and
bringing products to market through the rigorous FDA approval process. Since
2002, Dr. Ryan served as the Chief Executive Officer of RFR Consulting where he
focused on helping businesses in the biotech industry through providing
information, grant writing, business management, scientific guidance, FDA
regulatory advice, advising investors, and investment acquisition opportunities.
With 25 years experience including excellent training at the Wistar Institute,
NIH, and NCI, he has participated in basic and clinical investigations and has
published and edited research articles in several peer-reviewed journals.
Dr. Gerald W. Crabtree, COO:
Dr. Crabtree was recently named the Chief Operating Officer. Even in such a
short period as a few weeks, he has provided a significant benefit and impact
for Nuvilex, clearly matching not only the commitment to repositioning Nuvilex
into the biotechnology area, but also adds to the strength of our existing
products and pipeline. I have worked with Dr. Crabtree and look forward to
working with him to move Nuvilex forward. He has extensive experience in the
areas of natural and synthetic drug and device research and development, having
worked in both academia and small and large company environments. His business
and financial acumen together with his research and development background
combine to make him an invaluable addition to Nuvilex.
Since 1985, Dr.
Crabtree has been involved with various biopharmaceutical companies where he has
alternatively supervised and coordinated the development of multiple drug
candidates, prepared clinical protocols, investigator brochures, monographs,
research and review articles, and served as project manager for development of
major oncologic agents. He is a Member of the American Society of Clinical
Oncology and also is a past member of research grant review committees for the
National Institute of Health and the American Cancer Society. Dr. Crabtree
established and directed, from inception, a department that monitored and
coordinated the development of oncologic and immunologic drugs from initial
discovery through regulatory approval in a major pharmaceutical company and
served as project manager for the development of the anticancer agent,
Taxol®.
Dr. Crabtree received his Ph.D. in Biochemistry from the
University of Alberta, Edmonton, Alberta, Canada and has published over 80
articles in peer-reviewed journals. He is a National Cancer Institute of Canada
Research Fellow. In addition, he served as Department Head of Molecular
Pharmacology for the Nucleic Acid Research Institute and prior to that as
Associate Professor of Medicine with the Roger Williams Cancer Center at Brown
University. He has also served as Director of Project Planning and Management
(Oncology/Immunology) at Bristol-Myers Squibb and as Vice-President of Research
and Development at ETEX Corporation. Most recently, Dr. Crabtree served as
Interim CEO of PhytoCeutica, Inc., where he assisted in preparation and review
of FDA documents, clinical study protocols, investment acquisitions, and
contracts and business plans.
Patricia Gruden, Chairman of the Board of Directors and CFO:
Ms. Patricia Gruden has made a substantial impact in many companies over the
years. It was in 1995 that she became cofounder of the company that has since
become Nuvilex. The original company was initiated to develop a software program
through accurately tracking produce from the field to the table, including the
challenges of shipping, temperature variation and maintenance, and everything
else concerning the distribution of produce worldwide. In addition, the company
developed an ozone cleaning system to kill bacteria on produce without leaving
harmful residue on the product and without harming the environment. The company
and its footprint expanded, eventually giving rise to the start of the publicly
traded Nuvilex, Inc. Company's roots in 2001.
Ms. Gruden has carried out
almost every job in the company over the years including developer, shipper,
President, CEO, Chairman of the Board, CFO and many others. As a result, she has
been intricately aware of all aspects of the company and its products throughout
its history. After a short semi-retirement in 2009-10, she returned with renewed
vigor and has since put in extensive effort and funding into returning the
business to its former capabilities. Although her history and training has been
focused in management and sales, she clearly has made substantial advances for
Nuvilex.
Her training has not only included the real world experiences of
running more than one company, but was well founded in her attainment of her
B.S. degree in Business at the University of Oklahoma. From there, things have
never been the same, propelling her to embrace every business opportunity with
excitement, clarity and focus. Through the years, Patricia has had a long
history of owning her own businesses, and doing so successfully, with her
strengths in working with people, marketing and management. As part of her
contribution and success at Nuvilex, she is President of some of the
subsidiaries including Cinnergen, Inc. where she ensures organization,
marketing, cash flow, and good management. Currently, Ms. Patricia Gruden is the
Chairman of the Board of Directors and CFO for Nuvilex, guaranteeing a good dose
of knowledge and success for the company through efficient and thoughtful
oversight of the entire company and good fiscal management of our assets.